Reporting Animal Studies: Good Science and a Duty of Care

Reporting Animal Studies: Good Science and a Duty of Care

Estimates of the number of non-human animals used in research vary between 10 million and 50 million [1,2]. As a publisher, we receive submissions from scores of research groups in numerous different countries that report experimental results or observational data about a huge variety of organisms. Each field, each location, each type of experiment, and each organism may carry a different set o...

Open Science and Reporting Animal Studies: Who's Accountable?

What responsibility do scientists have to report the experimental work and analyses they do on animals fully and transparently, and what responsibilities do funders, journal editors, and reviewers have to ensure that what is reported is done so appropriately? While the answer to both of these questions might seem obvious, the accumulating evidence suggests that the actual reporting done in publ...

postnatal studies of bats (pipistrellus kuhlii and miniopterus schreibersii) & histomorphology and histochemistry studies of organs and diseases of (neurergus microspilotus and n. kaiseri)

1. to determine whether difference in birth body mass influenced growth performance in pipistrellus kuhlii we studied a total of 12 captive-born neonates. bats were assigned to two body mass groups: light birth body mass (lbw: 0.89 ± 0.05, n=8) and heavy birth body mass (hbw: 1.35 ± 0.08, n=4). heavier body mass at birth was associated with rapid postnatal growth (body mass and forearm length) ...

Reporting of Results from Animal Studies

One of the key elements of the scientific process is reproducibility: Experimental results generated in one laboratory must be repro­ ducible by others working independently. Therefore, it is of concern to us as editors of a major scientific journal to learn that only 6 of 53 " landmark " preclinical cancer studies could be reproduced (Begley and Ellis 2012). In addition, Prinz et al. (2011) re...

Good science with less animal experimentation